As much as Adwords is an incredible advertising delivery mechanism, it can only ever be as good as your advertising itself. In this video Youtube and TED asks the creators of some of the most popular viral videos of last year the question: "What makes ads worth spreading?"
This is one of those videos that I love to hate...Google's Chief Economist Hal Varian, (very simply) discusses advanced bidding strategies for maximising your profit using Google Adwords.